VA Cooperative Studies Program (CSP)

What's new in CSP?

• Article (06/05/2019) - CSP #465-F: VA Diabetes Trial Follow-up Study (VADT-FS) - Tight Diabetes Control Alone May Not Benefit the Heart Long-Term. Via U.S. News and World Report online.

• Article (05/01/2019) - Applied Proteogenomics Organizational Learning and Outcomes (APOLLO) – May 1, 2019, VA and partners hope APOLLO program will be leap forward for precision oncology - Large-scale research effort involves VA, Department of Defense, National Cancer Institute. - Via ORD VA Research Currents online.

• Press Release (06/19/2018) - VA Showcases New Medical Advancements in Veteran Care on Capitol Hill. WASHINGTON — Today the U.S. Department of Veterans Affairs’ (VA) Office of Research and Development hosted a Research Fair at the Rayburn House Office Building on Capitol Hill to share new medical advancements in improving health care and quality of life for Veterans across the nation. “VA has a long and distinguished history of health-care research leading to new discoveries and innovations to benefit Veterans and all Americans,” said Acting VA Secretary Peter O’Rourke. “VA continues to conduct cutting-edge research, such as the development and testing of advanced prosthetic limbs, the Million Veteran Program (MVP), precision-medicine initiative and regenerative medicine aimed at repairing severed spinal cords.” The event featured exhibits and demonstrations covering areas such as prosthetics, robotics, genomics and mental health. In the past, VA research has contributed to groundbreaking advances in medical care and technology, such as the CT scan, the cardiac pacemaker and the first successful liver transplant. “VA research has resulted in three Nobel prizes, seven Lasker awards and numerous other national and international honors,” said Dr. Carolyn Clancy, executive in charge of VA’s Veterans Health Administration. “We are very proud of the impact our research collaborations has on the health of Veterans and the nation.” The event also featured more than a dozen leading VA researchers, including Dr. Rory Cooper, a pioneer in wheelchair and other adaptive technology; Dr. Ann McKee, an authority on traumatic brain injury and chronic traumatic encephalopathy; and Dr. JoAnn Kirchner, who directs efforts to bring innovative mental health treatments to Veterans.  For more information on VA research, visit research.va.gov.

• Major VA trial helps answer question of which heart bypass method is better, August 17, 2017. CSP #517/ ROOBY Trial. 

• Press Release - VA partners with Department of Energy on big-data initiative to improve health care for Veterans, May 1, 2017. Excerpt - VA and DOE Partnership -"WASHINGTON — Today the Department of Veterans Affairs (VA) and the Department of Energy (DOE) announced the formation of a new partnership focused on the secure analysis of large digital health and genomic data, or so-called “big data,” from the VA and other federal sources to help advance health care for Veterans and others in areas such as suicide prevention, cancer and heart disease, while also driving DOE’s next-generation supercomputing designs."

• Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years, Full Article or Abstract; Meta-Analysis that includes patient-level data from VA CSP #498 Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)(OVER); doi: 10.1002/bjs.10430, February 3, 2017. (International collaborative data-sharing effort)

• Longitudinal Examination of Posttraumatic Stress Disorder as a Long-Term Outcome of Iraq War Deployment, Jennifer J. Vasterling; Mihaela Aslan; Susan P. Proctor; John Ko; Brian P. Marx; Matthew Jakupcak; Paula P. Schnurr; Theresa Gleason; Grant D. Huang; John Concato, American Journal of Epidemiology 2016; doi: 10.1093/aje/kww151, November 16, 2016.

• Chlorthalidone Versus Hydrochlorothiazide: A New Kind of VA Cooperative Study, National Institutes of Health (NIH) Collaboratory, presentation on CSP #597, Frank A. Lederle, MD, Professor of Medicine, University of Minnesota’s Center for Chronic Disease Outcomes Research, and Minneapolis VA Health Care System. CSP Coordinating Center: MAVERIC, Boston VAMC, October 7, 2016. (Article + PowerPoint video)

• Million Veteran Program Reaches Key Milestone, 500,000th volunteer, August 17, 2016.

• Wanted: Half a Million More Veterans to Volunteer, Veterans Health Administration (VHA)/ va.gov, August 16, 2016.

• Large VA trial seeks critical answers on colorectal cancer screening (VA Cooperative Studies Program (CSP) CSP #577 - Colonoscopy vs. Fecal Immunochemical Testing in Reducing Mortality From Colorectal Cancer), VAntage Point, Official Blog of the U.S. Dept. of Veterans Affairs, August 11, 2016.

• VA's Million Veteran Program (Video), VA is expected to hit 1/2 million volunteers in MVP, Comments by Dr. J. Michael Gaziano MD, MPH, Director of MAVERIC, Donald E. Humphries, PhD, MVP Principal Investigator, YouTube/U.S. Dept. of Veterans Affairs, August 1, 2016.

• Science Matters: VA Cooperative Studies Program Seeks To Tackle Lung Cancer Head-On (Audio), By Phil Liles, 88.9 WCVE's/NPR, July 20, 2016.

• Million Veteran Program draws on the power of collaboration, By John Concato, MD, MS, MPH, July 14, 2016.

• APOLLO Network #CanServe Cancer Patients through Collaboration, The APOLLO Network — Applied Proteogenomics OrganizationaL Learning and Outcomes: "The collaboration brings together the scientific and technical capabilities and facilities in DoD’s Murtha Cancer Center, the VA’s Veterans Health System, and the NCI’s Clinical Proteomic Tumor Analysis Consortium." July 1, 2016.

• Hot on the trail of PTSD genes, VA Research Currents, June 21, 2016 (Comments by Dr. Joel Gelernter and Dr. Murray Stein CSP#575B/ PTSD).

• Integrating Randomized Comparative Effectiveness Research with Patient Care, Louis D. Fiore, MD, MPH, and Philip W. Lavori, PhD, June 2, 2016.

• Veterans Affairs funds massive lung Cancer treatment study at McGuire VA Medical Center, By Katie Demeria, April 29, 2016.

• How VA’s Million Veteran Program is supporting the precision medicine movement, Dr. David Shulkin, April 25, 2016.

• National Kidney Foundation Lecture - Linda Fried, MD, MPH will be presenting on " Lessons Learned from VA NEPHRON-D", (CSP#565), National Kidney Foundation Spring 2016 Clinical Meetings, April 28, 2016.

• Acting Chief Research and Development Officer, David Atkins, MD, MPH, has been named acting chief research and development officer for VA, effective April 1, 2016. Dr. Atkins will oversee VA's nationwide research enterprise, encompassing more than 2,000 active projects at more than 100 sites, with a total 2016 budget—including VA and non-VA support—of $1.8 billion.

• Dr. John Concato, MD, MPH, Director of CERC, and Dr. J. Michael Gaziano MD, MPH , Director of MAVERIC - Article: Inside the Drive to collect DNA from 1 million veterans and revolutionize medicine, StatNews.com, The Million Veteran Program, by Carl Zimmer, November 11, 2015.

• VA’s Million Veteran Program hits 400K Milestone, "WASHINGTON – The Department of Veterans Affairs’ (VA) Million Veteran Program (MVP) has enrolled its 400,000th Veteran volunteer, squarely putting it on track to become one of the world’s largest medical databases, linking genetic, clinical, lifestyle and military-exposure information, with the goal of learning more about the role of genes in health and disease," October 8, 2015.

• Publication Brief Cooperative Studies Program, October 2015, "Study Suggests War-Time Location Affests Prevalence of PTSD among Vietnam Era Women Veterans, Prevalence of Post-traumatic Stress Disorder in Vietnam-Era Women Veterans, JAMA Psychiatry, November 2015, Vol 72, No.11, (JAMA Psychiatry. 2015;72(11):1127-1134. doi:10.1001/jamapsychiatry.2015.1786).

• End of 'Trial and Error' Approach to Depression, Schizophrenia? (CSP#576 VAST-D), By Kenneth Bender (medscape.com), August 14, 2015.

• Veteran Genome Project Serves as an Early Test Bed for Customized Care, (VA) Million Veteran Program (MVP) "The VA's four-year-old initiative includes thousands of DNA sequences along with a dose of privacy know-how," by Dina Manron, Scientific American, July 23, 2015.

• Dr. Domenic Reda, PhD, Director of Hines CSPCC, has been elected as President-Elect of the Society for Clinical Trials (SCT) as of May 17, 2015.

• Five VA research centers receive prestigious quality-management certification, Cooperative Studies Program Feature Article: VA Office of Research & Development, September 14, 2012.

   

Updated May 2018

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