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VA Cooperative Studies Program (CSP)

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CSP #585: Gulf War Era Cohort and Biorepository


Investigator Access

What's Available

  • Participant contact information: The CSP #585 team can contact study participants on behalf of other Investigators regarding research opportunities  
  • Research data: De-identified individual participant data (SAS and text files format)
  • Biospecimens: Coded DNA collected from 1,275 from participants

Available Documentation 

Dates Data are Available 

  • Datasets currently available, no end date
  • Specimens available pending RFS (see Access Criteria below)

Access Criteria 

CSPEC Durham has a temporary moratorium on accepting requests for CSP 585 specimens until a Request for Specimens (RFS) is prepared that prioritizes requests for these limited specimens.  If you would like to be notified when the RFS is released, please contact
Requests for CSP #585 datasets are welcome. During study planning, please contact to arrange a consultation to discuss the proposed study and data access requirements.  

Study Characteristics 


  • To develop a cohort of U.S. Veterans who served in the military in 1990-1991
  • To create a data and specimen repository that can be used for future research
  • To test the feasibility of implementing a full-scale project of this kind

Era of Service

Gulf War (1990-1991)


All Veterans who served July 1990 - August 1991, regardless of deployment or VA user status

Study Design  

Prospective cohort

Time Period 

September 2014 - 2020




1,275 participants

Response Rate


Recruitment Method

10,184 Veterans identified by from the Department of Defense Manpower Data Center roster were contacted by mail, with an option to opt-out

Follow-up was conducted by phone to administer informed consent


$50 American Express gift card

Data Collected

  • Blood sample (10-ml)
  • Permission to access VA and non-VA medical records
  • Survey data included demographics, military service history, lifestyle behaviors, physical and mental health indicators, family characteristics, and family health

Data Collection Methods

  • Survey data were collected via a structured questionnaire
  • Blood specimens were collected by a trained phlebotomist who visited the Veteran’s home or convenient location

Funding Source 

VA Cooperative Studies Program (CSP)


Dawn Provenzale, MD, MS


Selected Publication 

Khalil L, McNeil RB, Sims KJ, Felder KA, Hauser ER, Goldstein KM, Voils CI, Klimas NG, Brophy MT, Thomas CM, Whitley RL, Dursa EK, Helmer DA, Provenzale DT. The Gulf War Era Cohort and Biorepository: A Longitudinal Research Resource of Veterans of the 1990-1991 Gulf War Era. Am J Epidemiol. 2018 Nov 1;187(11):2279-2291.

More Information